RESEARCH ARTICLE


The Immunoglobulin G Concentration in Colostrum and Blood Serum from Sarabi Calves in Iran



Fereydon Rezazadeh*, 1, Badrosadat Rahnoma2, Jalal Abdolalizadeh3, Ali Akbar Heidari4
1 Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
2 Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
3 Immunology Laboratory, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
4 Department of Statistics, Faculty of Mathematics, University of Tabriz, Tabriz, Iran


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© Rezazadeh et al.; Licensee Bentham Open

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran; Tel: (+98) 411 6378742; Fax: (+98) 411 6378743; E-mail: f_rezazadeh@tabrizu.ac.ir


Abstract

The objective of the present study was to measure immunoglobulin G (IgG) levels in colostrum and blood serum of Sarabi calves as a genetic source of Iran. IgG levels determined in the first colostrum after calving by a SRID kit and also in the blood serum by ELISA and SRID. Twenty colostrum samples were taken from cows' immediately after parturition and stored at -20 °C until analysed. Venous blood samples for determination of plasma IgG concentration were obtained from 20 calves immediately before colostrum administered and after 24 h, 48 h and 8 days of birth. The maximum, minimum and mean (± SE) levels of IgG in the colostrum samples were 17000, 2000 and 8825±1206 mg/dl, respectively. The IgG levels (Mean± SE) in blood serum of calves were 451±17, 493 ±16, 508±26, and 503±24 mg/dl before colostrum intake, 24 h, 48 h, and 8 days after birth, respectively. The maximum concentrations of IgG in the blood serum (by ELISA) were 634, 631, 697 and 696 mg/dl in different time-points, respectively. IgG concentration in 4 calves that measured by SRID were 180, 1138, 1017, and 897 mg/dl in different time, respectively. The results showed that plasma IgG in calves was lower than 10 g/l, indicating existence of failure of passive transfer (FPT) in all the studied animals. Therefore, the Sarabi calves are prone to present clinical signs of FPT syndrome.

Keywords: Colostrum, ELISA, IgG, Sarabi, SRID.